{"id":22446,"date":"2025-04-10T09:11:24","date_gmt":"2025-04-10T09:11:24","guid":{"rendered":"https:\/\/www.topro.nl\/topro-knowledge-base\/lower-risk-of-ketosis-and-earlier-pregnancy\/"},"modified":"2026-09-30T08:22:32","modified_gmt":"2026-09-30T08:22:32","slug":"lower-risk-of-ketosis-and-earlier-pregnancy","status":"publish","type":"post","link":"https:\/\/www.topro.nl\/en\/topro-knowledge-base\/lower-risk-of-ketosis-and-earlier-pregnancy\/","title":{"rendered":"Lower risk of ketosis and earlier pregnancy"},"content":{"rendered":"<h3>KetoDuo bolus in practice<\/h3>\n<p><strong>Energy shortage, &#8220;slepende melkziekte&#8221; and ketosis: different terms for the same problem. Calving demands a lot from a cow, both metabolically and hormonally. Even though good products and methods are available, energy shortage remains a common problem. But how effective are these solutions in practice? We are finding out for you.<\/strong><\/p>\n<p>Ketosis occurs in the first weeks after calving. In this period cows have a high energy requirement for milk production, but often not enough feed intake. As a result they break down fat reserves, which can lead to a build-up of ketones in the blood. Symptoms of ketosis are lower feed intake, sluggishness, weight loss and falling milk production. In severe cases a cow can even stop eating completely, with all the consequences that brings.<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<table width=\"100%\">\n<tbody>\n<tr>\n<td>\n<h4><em>The trial design<\/em><\/h4>\n<p><em>In autumn 2024 a trial was carried out on the effect of the KetoDuo bolus on the start of the new lactation. It looked at the BHB level (the ketone body beta-hydroxybutyrate) in the milk and at the risk of ketosis. Pregnancy in the following lactation was also analysed. 40 animals took part in the trial, divided into 2 groups:<\/em><\/p>\n<p><em>Control group: did not receive a KetoDuo bolus<\/em><br \/>\n<em>KetoDuo group: received 2 KetoDuo boluses about one week before calving<\/em><\/p>\n<p><em>External factors were identical for both groups.<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>The results show that cows that did not receive a KetoDuo bolus had a higher risk of ketosis in the first seven days after calving, especially on days 3 and 4. This difference is also visible in the BHB level in the milk. In week 4 after calving, this level was 28% higher in the control group than in the KetoDuo group.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-21047 size-large\" src=\"https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-1024x496.png\" alt=\"\" width=\"1024\" height=\"496\" srcset=\"https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-1024x496.png 1024w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-300x145.png 300w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-768x372.png 768w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-1536x743.png 1536w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-1600x774.png 1600w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-64x31.png 64w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1-600x290.png 600w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-BHBwaarde-1.png 1806w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-21050 size-large\" src=\"https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1-1024x533.png\" alt=\"\" width=\"1024\" height=\"533\" srcset=\"https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1-1024x533.png 1024w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1-300x156.png 300w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1-768x400.png 768w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1-1536x799.png 1536w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1-64x33.png 64w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1-600x312.png 600w, https:\/\/www.topro.nl\/wp-content\/uploads\/figuur-risico-op-melkziekte-1.png 1539w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>It was also noticeable that the animals in the KetoDuo group got pregnant 10% faster than the control group. The difference was about 3 weeks, which indicates that the animals got pregnant 1 cycle sooner than the control group.<\/p>\n<p>So the KetoDuo bolus helps reduce the negative energy balance in the first weeks after calving, and it also contributes to cows getting pregnant sooner.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>KetoDuo bolus in practice Energy shortage, &#8220;slepende melkziekte&#8221; and ketosis: different terms for the same problem. Calving demands a lot [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1398,1398,747,747],"tags":[],"class_list":["post-22446","post","type-post","status-publish","format-standard","hentry","category-dairy-cattle","category-topro-knowledge-base"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Lower risk of ketosis and earlier pregnancy - Topro Animal Health<\/title>\n<meta name=\"description\" content=\"The KetoDuo bolus helps fresh cows with their energy balance. But what do we measure in cows that have had the KetoDuo bolus? 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